Ginkgo Biloba

INCI Name: Ginkgo Biloba ExtractPart Used: Leaves

Chemistry: 24% Flavonoids (ginkgo flavoneglycosides), 6% Terpene Lactones

Plant Description:
The ginkgo or maidenhair tree is the oldest known living tree species and last survivor of its botanical family Ginkgoaceae. It may grow to 80 feet and live as long as 1,000 years. Native to Asia, it is now found commonly in North America. The tree produces green to yellow fan-shaped leaves with radiating veins, and round fruit that contains a single seed.
Studies have indicated the following attributes:
Topical Application Improves Microcirculation: (1)
Protects capillaries against fragility, increases blood flow and metabolism efficiency, boosts oxygen levels to improve circulation-related disorders such as varicose veins and skin disorders
Potent Antioxidant: (2,3,5) Promotes healing of skin
and protects against aging of skin Anti-inflammatory (3,4,5,8) Protects Against Sun Damage: (6) Topical use inhibits
UVB irradiation skin damage Reduces Reaction to Contact Allergy Dermatitis: (7)
with topical use Enhances Synthesis of Collagen and Fibronectin: (8)
suggests it is protective against various tissue injuriesApplications: Skin CareReferences:

  1. Bombardelli E, Cristoni A, “Activity of phospholipid complex of Ginkgo biloba dimeric flavonoids on the skin microcirculation”, Fitoterapia, Vol LXVII No 3; 1996
  2. Valeria M Di Mamro, Maria J.V. Fonseca, “Assays of physical stability and antioxidant activity of a topical formulation added with different plant extracts”, Journal of Pharmaceutical and Biomedical Analysis, 37, 287-295; 2005
  3. Hibatallah J, Carduner C, Poelman MC, “In vivo and in-vitro assessment of the free-radical-scavenger activity of Ginkgo flavone glycosides at high concentration”, J Pharm Pharmacol, Dec. 51(12); 1435-40, 1999
  4. Pang Z, Pan F, He S, “Ginkgo biloba L: History Current Status, and Future Prospects”, The Journal of Alternative and Complementary Medicine”, Vol 2, No 3; 359-363; 1996
  5. Bederecioglu M, Tercan Mustafa, Ozyagan Irfan, “The Effect of Ginkgo Biloba Extract (Egb761) as a Free Radical Scavenger on the Survival of Skin Flaps in Rats”, Scand J Plastic Reconstruction Hand Surgery, 32:135-139, 1998
  6. Lin, Shan-Yang, Chang, Hone-Ping, “Induction of Superoxide Dismutase and Catalase Activity in Different Rat Tissues and Protection From UVB Irradiation After Topical Application of Ginkgo Biloba Extracts”, Methods Find Exp Clin Pharmacology, 19:(6), 367-71; 1997
  7. Castelli D, Colin L, Camel E, Reis G, “Pretreatment of skin with a Ginkgo biloba extract/sodium carboxymethyl-b-1,3-glucan formulation appears to inhibit the elicitation of allergic contact dermatitis in man”, Contact Dermatitis, 38(3); 123-6
  8. Kim SF, “Effects of Flavonoids of Ginkgo Biloba on Proliferation of Human Skin Fibroblast”, Skin Pharmacology, 10;200-205; 1997