Milk Thistle Attributes: |
Studies have indicated the following:
Powerful anti-oxidant. Scavenges free radicals.
Inhibits Photoaging (2,4,9)
Provides substantial UVB protection (1,3,4,5,6)
– Protects Epidermal Keratinocytes
– Stimulates DNA repair
Protects against UVA induced oxidative damage (7)
Anti-inflammatory (1,4,8)
Skin Lightening effect – Melanin Reduction (8)
Moisturizing, inhibits transepidermal water loss (9)
Smoother skin (9) |
References: |
- Katiyar, Santosh K, Korman, Neil J, et al, “Protective Effects of Silymarin Against Photocarcinogenesis in a Mouse Skin Model”, Journal of the National Cancer Institute, Vol 89 556-566, 1997
- Moushumi Lahiri-Chatterjee, Santosk K Katiyar, et al, ” A Flavonoid Antioxidant Silymarin, Affords Exceptionally High Protection against Tumor Promotion in the SENCAR Mouse Skin Tumorigenesis Model”, Cancer Research, 59 622-632, 1999
- Katiyar SK, Mantena SK, Meeran SM, “Silymarin protects epidermal keratinocytes from ultraviolet radiation-induced apoptosis and DNA damage by nucleotide excision repair mechanism”, PLoS One; 6(6):e21410. Epub 2011
- Vaid M, Katiyar SK, “Molecular mechanisms of inhibition of photocarcinogenesis by silymarin, a phytochemical from milk thistle (Silybum marianum L. Gaertn.), Int J Oncol. 36 (5); 1053-60, May 2010
- Katiyar SK, Meleth S, Sharma SD, “Silymarin, a flavonoid from milk thistle (Silybum marianum L.) inhibits UV-induced oxidative stress through targeting infiltrating CD11b+ cells in mouse skin”, Photochem Photobiol. 84(2): 266-71, Mar-Apr 2008
- Singh PR, Agarwal R., “Cosmeceuticals and silibinin”, Clin Dermatol. 27(5): 479-84, Sept-Oct 2009
- Alena Svobodova, Adela Zdarilova, et al, “Flavonolignans from Silybum marianum moderate UVA-induced oxidative damage to HaCa T keratinocytes.” Journal of Dermatological Science; 48, 213-224, 2007
- Akhtar Rasul, Naveed Akhtar, et al, “Assessment of anti erythmic and skin whitening effects of milk thistle extract”, African Journal of Pharmacy and Pharmacology Vol. 5(20), 2306-2309, Nov 2011
- Akhtar Rasul, Naveed Akhtar, “Anti-aging potential of a cream containing milk thistle extract: Formulation and in vivo evaluation”, African Journal of Biotechnology, Vol 11 (6) 1509-1515, Jan 2012
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